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This is called the founder effect. Indeed, all crossbreeding research involving North American breeds and strains is very dated McAllister, if it exists at all. Historical analysis indicated that a population expansion from just two matrilineal lines was responsible for most of the individuals within the population. Children of parent-child or sibling-sibling unions are at an increased risk compared to cousin-cousin unions. Inbreeding history of the population should also be considered when discussing the variation in the severity of inbreeding depression between and within species. In many cases, the closest available mate is a mother, sister, grandmother, father, brother, or grandfather.

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